Sex, Age, and Comorbidities Are Associated with SARS-CoV-2 Infection, COVID-19 Severity, and Fatal Outcome in a Mexican Population: A Retrospective Multi-Hospital Study.

People with comorbidities and the male sex are at a higher risk of developing severe COVID-19. In the present study, we aim to investigate the associated factors for infection, severity, and death due to COVID-19 in a population from Nuevo León, México. Epidemiological COVID-19 data were collected from 65 hospitals from December 2020 to May 2022. A total of 75,232 cases were compiled from which 25,722 cases were positive for SARS-CoV-2. Male sex, older age, diabetes, obesity, and hypertension were associated with infection. In addition to the above-mentioned factors, renal disease, cardiovascular disease, and immunosuppression were found to be associated with increased COVID-19 severity. These factors, as well as neurological diseases, are also associated with death due to COVID-19. When comparing the different variants of SARs-CoV-2, the variant B1.1.519 increased the probability of death by 2.23 times compared to the AY.20 variant. Male sex, older age, diabetes, obesity, and hypertension are associated with SARS-CoV-2 infection, severity, and death. Along with the aforementioned comorbidities, renal disease, cardiovascular disease, and immunosuppression are also associated with severity and death. Another factor associated with death is the presence of neurological disease. The SARS-CoV-2 B1.1.519 variant increases the odds of death compared to the SARS-CoV-2 AY.20 variant.

Risk Factors for SARS-CoV-2 Infection, Pneumonia, Intubation, and Death in Northeast Mexico.

Despite the social distancing and mobility restriction measures implemented for susceptible people around the world, infections and deaths due to COVID-19 continued to increase, even more so in the first months of 2021 in Mexico. Thus, it is necessary to find risk groups that can benefit from more aggressive preventive measures in a high-density population. This is a case-control study of suspected COVID-19 patients from Nuevo León, Mexico. Cases were: (1) COVID-19-positive patients and COVID-19-positive patients who (2) developed pneumonia, (3) were intubated and (4) died. Controls were: (1) COVID-19-negative patients, (2) COVID-19-positive patients without pneumonia, (3) non-intubated COVID-19-positive patients and (4) surviving COVID-19-positive patients. ≥ 18 years of age, not pregnant, were included. The pre-existing conditions analysed as risk factors were age (years), sex (male), diabetes mellitus, hypertension, chronic obstructive pulmonary disease, asthma, immunosuppression, obesity, cardiovascular disease, chronic kidney disease and smoking. The Mann-Whitney U tests, Chi square and binary logistic regression were used. A total of 56,715 suspected patients were analysed in Nuevo León, México, with 62.6% being positive for COVID-19 and, of those infected, 14% developed pneumonia, 2.9% were intubated and 8.1% died. The mean age of those infected was 44.7 years, while of those complicated it was around 60 years. Older age, male sex, diabetes, hypertension, and obesity were risk factors for infection, complications, and death from COVID-19. This study highlights the importance of timely recognition of the population exposed to pre-existing conditions to prioritise preventive measures against the virus.

Ética periodística y Covid-19: análisis de contenido de los códigos deontológicos / Ética jornalística e Covid-19: análise de conteúdo de códigos deontológicos / Journalistic ethics and Covid-19: an analysis of deontological codes

Esta investigación realiza un análisis de contenido de 103 códigos de ética periodística de todo el mundo para comprobar su adaptación a las circunstancias derivadas de la pandemia Covid-1٩. A partir de siete recomendaciones formuladas por la Ethical Journalism Network (EJN), se analiza su presencia o ausencia en los códigos. Los resultados muestran una presencia desigual de los principios y diferencias importantes entre los códigos. Ninguno de ellos comprende las siete recomendaciones y solo uno asume seis de ellas. Por el contrario, 17 códigos contienen únicamente una recomendación y dos de ellos no recogen ninguna. Se concluye que las recomendaciones de la EJN más presentes en los códigos se relacionan con principios muy asentados en la ética periodística que dependen habitualmente de la fecha de actualización. Se propone incorporar secciones específicas sobre salud a los códigos. (AU)

This article presents the results of a content analysis of 103 journalistic codes of ethics throughout the world conducted to test the adaptation of these codes to Covid-19 pandemic. Based on seven recommendations formulated by the Ethical Journalism Network (EJN), we analyze the presence or absence of each principle. The findings show an uneven presence of the principles and important differences across the codes. None of the codes cover the seven recommendations and just one addressed six of them. In contrast, 17 codes contain only one recommendation and two do not contain any. The EJN recommendations that are most present in the codes address well-established principles in journalistic ethics. The year of the latest update of the code is also a determining factor. Specific sections on health should be incorporated into the codes. (AU)

Esse artigo desenvolve uma análise de conteúdo de 103 códigos jornalísticos de ética em todo o mundo para testar sua adaptação às circunstâncias da Covid-19. Com base nas sete recomendações formuladas pela Ethical Journalism Network (EJN), analisa a presença ou ausência de cada princípio. Os resultados mostram uma presença desigual de princípios e importantes diferenças entre os códigos. Nenhum deles entende as sete recomendações e apenas uma assume seis delas. Em contraste, 17 códigos contêm apenas uma recomendação e dois deles não contêm nenhum. Conclui-se que as recomendações da EJN mais presentes nos códigos dizem respeito a princípios muito estabelecidos na ética jornalística. O ano da última atualização do código também se torna um fator determinante. Propõe-se incorporar seções específicas de saúde nos códigos. (AU)

De la lucha al testimonio. Las representaciones audiovisuales e interactivas del cáncer en los videojuegos / From fight to testimony. Audiovisual and interactive representations of cancer in video games / Da luta ao testemunho. Representações audiovisuais e interativas do câncer em videogames

Esta investigación explora la intersección entre el cáncer -una de las principales causas de mortalidad de las sociedades contemporáneas- y uno de los medios más significativos de la cultura popular en el siglo XXI: los videojuegos. El análisis de contenido de los mensajes ha comprendido ocho videojuegos que, durante los últimos 15 años, revelan un planteamiento narrativo en torno a la afección, pacientes, tratamientos y desenlace de la enfermedad. Los resultados señalan una construcción en la que perviven sus rasgos más populares dirigidos al empoderamiento social frente a la enfermedad a través del recurso a la ciencia, el respaldo social o las convicciones espirituales.(AU)

This article analyzes the intersection between cancer - one of the leading causes of death in contemporary society - and one of the most important forms of media in twentieth-century popular culture: video games. An analysis was conducted of messages conveyed by eight videogames launched in the last 15 years with narratives on the disease, patients, and cancer treatment and outcomes. The findings point to a narrative construction that depicts the most common features of the disease, focusing on social empowerment through the use of science, social support, and spiritual convictions.(AU)

Neste artigo analisamos a interseção entre o câncer - uma das principais causas de mortalidade nas sociedades contemporâneas - e uma das mídias mais significativas da cultura popular no século 21: os videogames. A análise de conteúdo das mensagens foi composta por oito videogames que, nos últimos 15 anos, revelam uma abordagem narrativa em torno da condição dos pacientes, dos tratamentos e do desfecho da doença. Os resultados apontam para uma construção em que permanecem seus traços mais populares, voltados para o empoderamento social frente à doença, por meio do uso da ciência, apoio social ou das convicções espirituais.(AU)

Detección de problemas geriátricos no conocidos en adultos mayores de Nuevo León / Detecting unknown geriatric problems in the elderly of Nuevo León

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Fortalecimiento de la atención primaria del adulto mayor ante la transición demográfica en México / Strengthening the primary care of the elderly due to the demographic transition in Mexico

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Mortality predictive indexes in non-critical inpatients.

BACKGROUND: Mortality predictive indexes have not been applied to patients in general wards out of the ICU. METHODS: Retrolective study aimed to evaluate the value of mortality prediction indexes in a cohort of 944 non-critical patients. Three indexes were evaluated according to their calibration and discriminative power: the Mortality Probability Model II (MPMII), the Simplified Acute Physiology System II (SAPS II) and the Logistic Organ Dysfunction System (LODS). The bivariate calculation of relative risk (RR) to die was performed relative to the group of patients that had an expected probability to die > 10%, calculated by an index. To evaluate the calibration, data were arranged in descending order using the chi2 goodness-of-fit model. To evaluate discrimination power, ROC curves were used. RESULTS: SAPS II, MPM II and LODS predicted significant risks at levels of P < 0.005, (RR = 6.56, 4.03 and 3.44, respectively). Regarding the calibration, the null hypothesis was accepted only by using SAPS II (P = 0.664). CONCLUSIONS: The three evaluated indexes each had a good discriminative capacity to detect non-critical inpatients with high risk to die. SAPS II was the best index to predict mortality, as determined by both the bivariate and the calibration analysis. There is no reason for not using mortality predictive indexes for non-critical inpatients.